Creatinine (GFR)

Message
Performing Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields


Test Code
3711


Alias/See Also
Sunquest: GFR; Glomerular Filtration Rate, Creatinine


CPT Codes
82565

Includes
Creatinine, GFR


Preferred Specimen
0.1 mL Lithium Heparin Plasma (light green-top) tube


Minimum Volume
70 uL


Other Acceptable Specimens
Serum (gold-top, red-top, red/gray-top), Lithium Heparin (light green-top) on ICE


Transport Temperature
Refrgerated


Specimen Stability

Room Temperature (7 days), Refrigerated (7 days), Frozen (3 months)


Methodology

    Enzymatic
GFR: Calculated using the CKD-EPI-eGFR equation utilizing serum Creatinine (traceable to IDMS), age, sex, and race as variables.

Setup Schedule
Hospital: Daily
Clinics: Monday - Friday


Report Available
Same day.


Limitations
GFR and Creatinine both reported on patients >18 years
Creatinine only is reported on patients <18 years


Reference Range
 
 
 
Gender Age Ref. Range Critical
Both 0 - 16 years 0.55 - 1.18 mg/dL >=2.0 mg/dL
Female >=16 years 0.55 - 1.02 mg/dL >=7.0 mg/dL
Male >=16 years 0.73 - 1.18 mg/dL >=7.0 mg/dL

GFR (>=20 Years): >60mL/min/1.732
 


Clinical Significance
Serum creatinine and urinary creatinine excretion is a function of lean body mass in normal persons and shows little or no response to dietary changes. The serum creatinine concentration is higher in men than in women. Since urinary creatinine is excreted mainly by glomerular filtration, with only small amounts due to tubular secretion, serum creatinine and a 24-hour urine creatinine excretion can be used to estimate the glomerular filtration rate.

Serum creatinine is increased in acute or chronic renal failure, urinary tract obstruction, reduced renal blood flow, shock, dehydration, and rhabdomyolysis. Causes of low serum creatinine concentration include debilitation and decreased muscle mass.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.