Hepatitis B Surface Antigen High Risk Cascade

Message
Performing Lab: Central Lab


Test Code
3715


Alias/See Also
Sunquest: HBSR


CPT Codes
87340

Includes
Reflex testing if positive: Hepatitis B Quantitative DNA by Real-Time PCR; Hepatitis Be Antigen; Hepatitis Be antibody
Reflex testing if negative: Hepatitis B surface antibody; Hepatitis B core total antibody


Preferred Specimen
3.0 mL Serum Separator FULL (Tall gold-top) tube


Minimum Volume
3.0 mL


Transport Temperature
Refrigerated


Specimen Stability
Refrigerated: 7 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis


Methodology
Chemiluminescence Immunoassay

Setup Schedule
Monday - Friday


Report Available
2 Business Days


Limitations
High risk includes patients with a history of IV drug abuse, history of STD’s, multiple sex partners, sex partners with known Hepatitis B disease, patients infected with HIV, homosexual contact, exposure to known contaminated blood or blood products, history of a needle stick exposure, and ethnicity/country of birth from areas of the world with a high rate of HBV endemicity. HBsAg Risk Cascade testing reflexes into two different algorithms depending on if reported as Negative (Non-Reactive) or Positive (Reactive).


Reference Range
Negative (Non-reactive)


Clinical Significance
HBsAg is a protein produced by the Hepatitis B Virus (HBV) and is the earliest indicator of acute Hepatitis B. In some people, chronic infection with HBV may occur and HBsAg remains positive for a long period of time. When this occurs, other tests may be helpful to distinguish Hepatitis B carrier status, such as Hepatitis Be Antigen, Hepatitis Be Antibody and Hepatitis B DNA Quantitative PCR. HealthPartners offers multiple Hepatitis B surface antigen codes.
• Epic Test code # 4607 (Sunquest code HBsAg, No Reflex) does not reflex to any testing.
• This Hepatitis B surface Antigen test code (Epic # 0186) is helpful for screening in pregnancy and provides reflex testing when reported as Positive (Reactive).
• For any patients considered to be at high risk for Hepatitis B infection, Physicians should order the test named: HBsAg Risk Cascade (Sunquest code HBSR / Epic # 3715). High risk includes patients with a history of IV drug abuse, history of STD’s, multiple sex partners, sex partners with known Hepatitis B disease, patients infected with HIV, homosexual contact, exposure to known contaminated blood or blood products, history of a needle stick exposure, and ethnicity/country of birth from areas of the world with a high rate of HBV endemicity. HBsAg Risk Cascade testing reflexes into two different algorithms depending on if reported as Negative (Non-Reactive) or Positive (Reactive).




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.