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Carbamazepine
MessagePerforming Lab: Lakeview, Regions, Westfields
Test Code
0205
Alias/See Also
Sunquest: CARBA; Tegretol, Carbamazepine Total, Carbatrol
CPT Codes
80156
Includes
Time of last dose; Carbamazepine
Preferred Specimen
0.2 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
0.1 mL
Other Acceptable Specimens
Serum separator (gold-top), Red, Red/Gray
Instructions
Ordering:
If Epoxide is also requested, see EPOXS.
If Epoxide is also requested, see EPOXS.
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 5 days
Refrigerated: 5 days
Frozen: 6 months
Refrigerated: 5 days
Frozen: 6 months
Methodology
Multi-point Immunorate
Setup Schedule
Daily
Report Available
Same day.
Limitations
Specimens with a low total protein (<4.0 g/dL) may give a negative bias.
Specimens with an elevated total protein (>9.0 g/dL) may give a positive bias.
Specimens with an elevated total protein (>9.0 g/dL) may give a positive bias.
Reference Range
4.0 - 12.0 µg/mL
Critical: >= 15 µg/mL
Critical: >= 15 µg/mL
Clinical Significance
Carbamazepine is a commonly prescribed anti-convulsant used mainly in the treatment of seizure disorders, but is also used to treat trigeminal neuralgia. Carbamazepine has also been useful in the treatment of manic depressive patients as an alternative to lithium therapy. Carbamazepine measurements are used to monitor patient compliance and therapy, and to diagnose potential overdose.
