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C-Reactive Protein
MessagePerforming Lab: Central Lab, Hudson, Lakeview, Regions, Sartell, Westfields
Test Code
0236
Alias/See Also
Sunquest: CRP
CPT Codes
86140
Preferred Specimen
0.1 mL Lithium Heparin Plasma (light green-top) tube
Minimum Volume
52 uL
Other Acceptable Specimens
Serum separator (gold-top), Red, Red/Gray
Transport Temperature
Refrgerated
Specimen Stability
Room Temperature (36 hours), Refrigerated (2 months), Frozen (3 years)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis
Methodology
Turbidimetric/Immunoturbidimetric
Setup Schedule
Hospital: Daily
Clinics: Monday - Friday
Clinics: Monday - Friday
Report Available
Same day.
Limitations
Specimens with a low total protein (<4.9 g/L) may give a positive bias while specimens with an elevated total protein (>9.5 g/L) may give a negative bias.
Reference Range
0.0 - 0.7 mg/dL
Clinical Significance
C-reactive protein is synthesized by the liver and is one of the acute phase proteins. In the acute phase response, increased concentrations of a number of plasma proteins, including CRP, are observed. CRP concentration measurements are useful in the detection and evaluation of inflammatory disorders, tissue injury, and infections.
