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Digoxin
MessagePerforming Lab: Hudson, Lakeview, Regions, Westfields
Test Code
0201
Alias/See Also
Sunquest: DIG; Lanoxin
CPT Codes
80162
Includes
Time of Last Dose, Digoxin
Preferred Specimen
0.2 mL Serum Separator (gold-top) tube
Minimum Volume
0.1 mL
Other Acceptable Specimens
Red, Red/Gray
Instructions
Collection:
Digoxin specimens should be drawn at least six to eight hours after the last dose. If toxicity is suspected, specimens may be drawn at any time.
Digoxin specimens should be drawn at least six to eight hours after the last dose. If toxicity is suspected, specimens may be drawn at any time.
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 8 hours
Refrigerated: 1 week
Frozen: 4 months
Refrigerated: 1 week
Frozen: 4 months
Methodology
Multi-point Immuno-rate or Immunoassay/Bichromatic Rate (Lakeview)
Setup Schedule
Daily
Report Available
Same day.
Limitations
The Digoxin Immune FAB (Digibind), which is used in the treatment of digoxin intoxication, has been found to interfere with immunoassay measurments. Digoxin measurments in patients that have been administered Digibind should be interpreted with caution.
Reference Range
0.8 - 2.0 ng/mL
Critical: >= 2.5 ng/mL
Critical: >= 2.5 ng/mL
Clinical Significance
Digoxin is a widely prescribed cardiac glycoside indicated in the treatment of congestive heart failure and supraventricular arrhythmias. Digoxin measurements are used to monitor patient compliance and therapy, and to diagnose potential overdose.
