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Helicobacter pylori Antibody, IgG
MessagePerforming Lab: Central Lab, Regions
Test Code
2193
Alias/See Also
Sunquest: HELI; Helicobacter pylori IgG, H. pylori
CPT Codes
86677
Preferred Specimen
1.0 mL Serum Separator (gold-top) tube
Minimum Volume
0.5 mL
Other Acceptable Specimens
Red, Red/Gray
Regions Only: EDTA plasma (lavander-top)
Regions Only: EDTA plasma (lavander-top)
Transport Temperature
Refigerated
Specimen Stability
Refrigerated: 7 days
Frozen: 2 months
Frozen: 2 months
Methodology
Hospital: Enzyme-Linked Fluorescent Immunoassay (ELFA) Central Lab: Enzyme Immunoassay (EIA)
Setup Schedule
Hospital: Daily
Clinics: Tuesday & Thursday
Clinics: Tuesday & Thursday
Report Available
Hospital: Results are reported the same day.
Clinics: Results are generally reported within 2-3 days of collection.
Clinics: Results are generally reported within 2-3 days of collection.
Limitations
The H. pylori antibody assay tests for an IgG Antibody and cannot distinguish current from past
infections. Alternative testing of H. pylori stool antigen testing (Sunquest code HPYA / Epic code 2634) is recommended when there is a need to distinguish past infection from current infection or when H. pylori antibody testing is reported as Equivocal or Inconclusive. Equivocal results may indicate a lack of antibody development to the H. pylori organism, or an antibody level that has faded throughout the years.
infections. Alternative testing of H. pylori stool antigen testing (Sunquest code HPYA / Epic code 2634) is recommended when there is a need to distinguish past infection from current infection or when H. pylori antibody testing is reported as Equivocal or Inconclusive. Equivocal results may indicate a lack of antibody development to the H. pylori organism, or an antibody level that has faded throughout the years.
Reference Range
Negative
Equivocal results may indicate a lack of antibody development to the H. pylori organism, or
an antibody level that has faded throughout the years. Repeat the testing if clinically indicated.
Equivocal results may indicate a lack of antibody development to the H. pylori organism, or
an antibody level that has faded throughout the years. Repeat the testing if clinically indicated.
Clinical Significance
It has been shown that infection with Helicobacter (formerly Camplyobacter) pylori, a spiral shaped microaerophilic bacillum, leads to inflammation of the stomach mucosa (gastritis) and in some infected persons, ulcers. The infection may also play a role in the development of stomach cancer. Symptomatic patients with H. pylori are considered infected, while asymptomatic people with H. pylori are considered colonized. Most people who are colonized with H. pylori never develop ulceration and remain asymptomatic despite colonization for years, probably even decades.
