LD (Lactate Dehydrogenase)

Message

Performing Lab: Central Lab,St Cloud, Hudson, Lakeview, Regions, Westfields

Test Code

0122

Alias/See Also

Sunquest: LD; LDH

CPT Codes
83615

Preferred Specimen

0.1 mL Serum (gold-top) tube

Minimum Volume

0.1 mL (All sites)

Other Acceptable Specimens

Serum ONLY

Transport Temperature

Room Temperature

Specimen Stability

Room Temperature (7 days), Refrigerated (4 days), Frozen (6 weeks)

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis

Methodology

IFCC recommended forward reaction - Lactate to Pyruvate

Setup Schedule

Hospital: Daily
Clinics: Monday - Friday

Report Available

Same day

Limitations

Unable to add on to samples that have been previously tested and stored either refrigerated or frozen.

Reference Range




	119 - 235 U/L

Clinical Significance

Lactate dehydrogenase is an enzyme present in the cytosol of all human cells; it catalyzes the reversible reduction of pyruvate to lactate using NADH. Causes of high LDH include neoplastic states, hypoxic cardiorespiratory diseases, myocardial infarctions, hemolytic anemias, megaloblastic anemias, hepatic cirrhosis, renal infarction, trauma, muscle damage, muscular dystrophy, shock, and hypotension. In myocardial infarction cases, LDH begins to rise within about 12 hours after infarction and usually returns to normal after two to five days.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.