Smith-Lemli-Opitz Screen, Plasma

Test Code

4485

Quest Code

15992

Alias/See Also

Quest 15992; Sunquest: SLOPS

CPT Codes
82542

Physician Attestation of Informed Consent

This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.

Includes

7-Dehydrocholesterol and 8-Dehydrocholesterol

Preferred Specimen

0.5 mL plasma collected in a sodium or lithium heparin (green-top) tube

Patient Preparation
Fasting (12 hours or more, infants just before next feeding)

Minimum Volume

0.2 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender top) tube, EDTA (pearl white-top) (plasma gel), or ACD (yellow-top) tube

Instructions

Spin down within 45 minutes of draw.

Forms: New York clients-informed consent is required.
Please document on the request form or electronic order that a copy is on file. An Informed Consent for Genetic Testing (T576) is available in special instructions.

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 14 days
Refrigerated: 28 days
Frozen: 90 days

Methodology
Gas Chromatography/Mass Spectrometry (GC/MS)

Setup Schedule

Batched, 1x per week

Report Available

3-9 days

Reference Range

7-Dehydrocholesterol	≤2.0 mg/L
8-Dehydrocholesterol	≤0.3 mg/L

Performing Laboratory

Mayo Clinical Laboratories

200 1st Street SW

Rochester, MN 55905-0001

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.