Nickel, 24-Hour Urine

Test Code

4386

Quest Code

36443

Alias/See Also

Quest 36443; Sunquest: NIU24

CPT Codes
83885

Includes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen

7 mL of a well-mixed 24-hour urine collected in an acid-washed or metal-free container

Minimum Volume

3 mL

Other Acceptable Specimens

Tests performed on a specimen submitted in a non-trace element tube or non acid-washed/non metal-free container may not accurately reflect the patient's level. If a non-trace element tube/container is received, it will be accepted for testing. However, elevated results shall be reported with a message that re-submission with a trace element tube/container is recommended.

Instructions

Avoid worksite collection. Collect urine in an acid-washed or metal-free plastic container.

Transport Container

Acid-washed plastic urine container

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 30 days
Frozen: 30 days

Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Mon-Fri

Report Available

2-4 days at performing lab

Reference Range

Occupationally non-exposed individuals	1.5-13.0 mcg/L
Healthy individuals in electroplating	10.0-120.0 mcg/L

Clinical Significance

Nickel toxicity is associated with allergy, asthma, urticaria, erythema multiforme, contact dermatitis, and hand eczema.

Performing Laboratory

Quest Diagnostics Nichols Institute-Chantilly VA

14225 Newbrook Drive

Chantilly, VA 20151-2228

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.