Varicella-Zoster Virus (VZV) Antibodies (Total, IgM), ACIF/IFA CSF [34972X]

Test Code

CPT Codes
86787 (x2)

VZV Antibody, Total, ACIF and VZV Antibody (IgM), IFA

Preferred Specimen
0.5 mL CSF collected in a sterile, leak-proof container

Minimum Volume
0.2 mL

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Anti-Complement Immunofluorescence (ACIF) • Indirect Fluorescent Antibody (IFA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues-Sat a.m.; Report available: 1-3 days

Reference Range
VZV Ab, Total ACIF, CSF <1:2
VZV Ab (IgM), IFA, CSF <1:1

Clinical Significance
Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

Performing Laboratory
Quest Diagnostics Infectious Disease, Inc
33608 Ortega Highway Building B
San Juan Capistrano, CA 92675

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.