Methemoglobin [647X]

Test Code

CPT Codes

May include a Hemoglobin level

Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume
0.5 mL

Specimen must be delivered within 72 hours of collection time for analysis.
Please note: Heparinized or citrated whole blood can also be used if client provides a hemoglobin result on the patient.

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 2 hours
Refrigerated: 72 hours (from collection time)
Frozen: Unacceptable

Spectrophotometry (SP)

Setup Schedule
Set up: Daily a.m.; Report available: 1 day

Reference Range

Clinical Significance
The Methemoglobin concentration in blood is increased to 10 to 30 percent of the total hemoglobin in congenital methemoglobinemia.

Methemoglobin is increased to some degree in persons who have ingested nitrites, nitrates, or certain drugs or chemicals such as phenacetin, phenazo-pyridine, sulfonamides, sulfones, or aniline dyes, as well as in those who have received a local anesthetic that contains an aniline ring, such as benzocaine or lidocaine.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.