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Herpesvirus 8 (HHV-8) DNA, Qualitative Real-Time PCR [19803X]
Test Code19803
CPT Codes
87798
Preferred Specimen
0.7 mL serum, or
0.7 mL plasma collected in an EDTA (lavender-top) tube, or ACD (yellow-top) tube
Minimum Volume
0.3 mL
Other Acceptable Specimens
Whole blood collected in an EDTA (lavender-top) tube, or ACD (yellow-top) tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Serum and plasma
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Whole blood
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: Unacceptable
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 1 day
Reference Range
Not detected
Clinical Significance
Human herpesvirus 8 (HHV-8) is associated with the development of all forms of Kaposi's sarcoma as well as with some other rare lymphoproliferative diseases, such as primary effusion lymphoma and multicentric Castleman's disease. Qualitative PCR is often used to aid in diagnosis of an HHV-8 infected individual.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153