Microsporidia Exam [3562X]

Test Code

CPT Codes

Smear and Concentration (if performed)

Preferred Specimen
5 grams or 5 mL stool submitted in 10% formalin container, or Total-Fix® transport vial

Minimum Volume
Stool or Duodenal fluid: 2 g or 2 mL
Urine, CSF, BAL: 2 mL

Other Acceptable Specimens
Duodenal fluid submitted in 10% formalin container, or Total-Fix® transport vial • Corneal scrapings submitted in a slide holder • Urine, or CSF, or bronchoalveolar lavage submitted in a sterile, leak-proof container

1. Stool duodenal aspirates fixed in 10% formalin or Total-Fix®.
2. Urine sediments, CSF, BAL/Nasal secretions: preferred in sterile container, acceptable on microscope slide, methanol (or 10% formalin).
3. Conjunctival/corneal scrapings, preferred on microscope slide, methanol (or 10% formalin). Ship preserved specimens at room temperature (preferred).

Transport Temperature
Stool or Duodenal fluid or Corneal scrapings: Room temperature
Urine, CSF, or BAL: Refrigerated (cold packs)

Specimen Stability
Stool, Duodenal, and Corneal scrappings
Room temperature: 30 days
Refrigerated: 30 days
Frozen: Unacceptable
Urine, CSF, and Bronchoalveolar lavage
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Unpreserved stool • Stool in Cary-Blair or PVA • Received frozen


Setup Schedule
Set up: Mon, Thurs a.m.; Report available: Next day

Reference Range
See Laboratory Report

Clinical Significance
Microsporidia infection was first recognized as a cause of chronic diarrhea in patients infected with HIV. Microsporidia may also cause pneumonia, acute bilateral keratoconjunctivitis, and infection of the biliary and pancreatic ducts.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.