JC Virus DNA, Ultrasensitive (LLOQ 10 copies/mL), Quantitative, Real-Time PCR, CSF

Test Code

CPT Codes

Preferred Specimen
1 mL frozen CSF submitted in a sterile, leak-proof container

Minimum Volume
0.5 mL

Transport Temperature

Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Real-Time Polymerase Chain Reaction (PCR)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon-Sat a.m.; Report available: 2-4 days

Reference Range
<10 copies/mL

Clinical Significance
JC polyoma virus is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunocompromised patients and patients on certain medications. This test detects and quantifies JCV in cerebrospinal fluid (CSF). Detection of the virus in CSF may indicate infection.

Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.