Adenovirus Culture [38929X]

Test Code
759


CPT Codes
87254

Preferred Specimen
3 mL fresh stool, throat swab, or conjunctiva submitted in VCM transport medium, or 50 mL first morning catch urine or 2.5 mL nasal wash/aspirate submitted in a sterile, leak-proof container


Minimum Volume
Fresh stool, throat swab, conjunctiva, bronchial or nasal wash/aspirate: 1 mL
Urine: 5 mL


Other Acceptable Specimens
3 mL nasal wash/aspirate or bronchial lavage/wash submitted in VCM transport media • Fresh stool, nasal wash/aspirate, conjunctiva or bronchial lavage/wash submitted in M4 transport media • 2.5 mL bronchial brush/wash submitted in a sterile, leak-proof container


Instructions
Body fluids to be submitted in VCM Transport Medium (preferred) must be mixed with an equal amount of the VCM Transport Medium. Do not place small volumes of fluid directly into the tube as this causes over-dilution of the specimen. M4 Transport Medium is acceptable.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Specimens in VCM or M4 Transport Medium
Room temperature: Unacceptable
Refrigerated: 4 days
Frozen -70°C: 30 days

Specimens in sterile, leak-proof container
Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: Unacceptable


Methodology
Centrifugation Enhanced Culture using R-mix cell line

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Daily a.m.; Report available: 4 days


Reference Range
Not isolated


Clinical Significance
Adenovirus is responsible for up to 10% of all febrile illness occurring in the first 2 years of life and 5% of febrile episodes in the 2-4 year age group. Adenoviruses are associated with a number of clinical syndromes including pharyngoconjunctival fever, acute febrile pharyngitis, epidemic keratoconjunctivitis and hemorrhagic cystitis. Virus can be detected in clinical specimens, usually during the first 3 days of illness. Rapid viral culture can provide definitive identification, which may assist in determining prognosis and appropriate therapy.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.