Tick-borne Disease, Acute Molecular Panel, Non-Lyme

Test Code
32338


Alias/See Also
LAB10022


CPT Codes
87468, 87469, 87478, 87484<br><strong>CPT coding may differ dependent on payer rules which may impact prior authorization testing.</strong><br><strong>Please direct any questions regarding CPT coding to the payer being billed.</strong>

Includes
Anaplasma Phagocytophilum DNA, Qualitative Real-Time PCR
Babesia microti DNA, Real-Time PCR
Borrelia miyamotoi DNA, Real-Time PCR, Miscellaneous
Ehrlichia chaffeensis DNA, Real-Time PCR


Preferred Specimen
3 mL whole blood collected in an EDTA (lavender-top) tube


Minimum Volume
1.5 mL


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received frozen • Heparin as an anticoagulant


Methodology
Real-Time Polymerase Chain Reaction

Setup Schedule
Set up and Report available: See individual assays


Reference Range
Anaplasma phagocytophilum DNA, QL Real Time PCR Not Detected
Babesia microti DNA, Real-Time PCR  Not Detected
Borrelia miyamotoi DNA, Real-Time PCR, Misc  Not Detected
Ehrlichia chaffeensis DNA, Real-Time PCR  Not Detected


Clinical Significance
Persons infected with Borrelia miyamotoi most likely have fever, joint pains, fatigue, and headache, though unlike Lyme disease, rash is uncommon.
The diagnosis of Borrelia miyamotoi is most often made by history and clinical examination combined with exposure in endemic areas. Amplification of B. miyamotoi genomic DNA from blood, fluids or tissues confirms the diagnosis.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.