Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel

Message

Important Note

Before collecting specimen(s) for this test, arrangements must be made with the Central Lab specimen processing department for Direct Shipping of the specimen to the performing laboratory due to short stability of the specimen.

Specimen should be collected as close to courier pickup as possible.

Test Code

30555

Alias/See Also

REFLB
Miscellaneous Quest Testing

Fatty,Steatohepatitis
NAFLD
FIB4
Steatosis,Nonalcoholic,NASH

CPT Codes
84450; 84460; 85049

Includes

Aspartate Aminotransferase (AST)
Alanine Aminotransferase (ALT)
Platelet Count
FIB 4 Index

Preferred Specimen

1 mL serum collected in a Serum Separator Tube (SST®) and whole blood full EDTA (lavender-top) tube

Minimum Volume

0.5 mL serum • 0.5 mL microtainer-lavender or 1 mL EDTA whole blood

Instructions

Ordering (SoftLab)

Place an order for REFLB.
In the Order Comments/Comment tab, enter:
DIRECT SHIP - Sent to Quest SJC, CA
Test: 3055 Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel
When prompted, for Quest Test Code and Specimen Type, enter SEE COMMENT.

Specimen Processing

Follow the instructions for IL Direct Shipping in Policy Stat to send specimen to SJC directly.

Transport Container

Serum Separator Tube (SST®) and EDTA (lavender-top) tube

Transport Temperature

Room Temperature

Specimen Stability

Serum
Room temperature: 72 hours
Refrigerated: 5 days
Frozen: Unacceptable

Whole blood
Room temperature: 48 hours

Methodology
Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy

Clinical Significance

Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel - The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4).

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675

Additional Information
IL Direct Shipping Process
Test Summary (Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel)
Viral Hepatitis: Laboratory Support of Diagnosis and Managemen
Laboratory Testing for Diabetes Diagnosis and Management

Last Updated: September 29, 2023
Last Review: N. Wolford, September 29, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.