Tick-borne Disease, Acute Molecular Panel

Test Code
TBDP


Alias/See Also
Epic: LAB13351
Quest: 94322


CPT Codes
87468, 87469, 87478, 87484, 87801<br>&#8288;&#8288;&#8288;&#8288;&#8288;&#8288;&#8288;<strong>CPT coding may differ dependent on payer rules which may impact prior authorization testing.</strong><br><strong>Please direct any questions regarding CPT coding to the payer being billed.</strong>

Includes
⁠⁠⁠⁠⁠⁠⁠Anaplasma Phagocytophilum DNA, Qualitative Real-Time PCR
Babesia microti DNA, Real-Time PCR
Borrelia miyamotoi DNA, Real-Time PCR,
Ehrlichia chaffeensis DNA, Real-Time PCR
Borrelia Species DNA, Qualitative Real-Time PCR


Preferred Specimen
3 mL whole blood collected in an EDTA (lavender-top) tube


Minimum Volume
1.5 mL


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Lithium heparin (green-top) tube • Sodium heparin (green-top) tube


Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: See individual tests; Report available: 1-3 days


Reference Range
See Laboratory Report


Clinical Significance
Persons infected with Borrelia miyamotoi most likely have fever, joint pains, fatigue, and headache, though unlike Lyme disease, rash is uncommon.
The diagnosis of Borrelia miyamotoi is most often made by history and clinical examination combined with exposure in endemic areas. Amplification of B. miyamotoi genomic DNA from blood, fluids or tissues confirms the diagnosis.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153


Last Updated: April 7, 2023
Last Review: N. Wolford, April 7, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.