Theophylline

Test Code
THEOP


Alias/See Also

LAB35



CPT Codes
<p>80198</p>

Preferred Specimen

Specimen Type: Serum


Collection Container/Type: Red top


Submission Container/Tube: Plastic vial


Specimen Volume: 1 mL


Collection Instructions: Collect as a trough just prior to next dose.


 


Specimen Type: Plasma


Collection Container/Type


Preferred: Lavender top (EDTA)


Acceptable: Green top (Lithium heparin or sodium heparin)


Submission Container/Tube: Plastic vial.


Specimen Volume: 1 mL


Collection Instructions: Collect as a trough just prior to next dose



Minimum Volume

0.2 mL



Other Acceptable Specimens
Plasma collected in: Sodium heparin (green-top) tube, lithium heparin (green-top) tube, or EDTA (lavender-top) tube


Instructions
Collect as a trough just prior to next dose.


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability

Room temperature: 6 days


Refrigerated: 7 days


Frozen: 90 days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tube (SST ®)



Methodology

Immunoassay (IA)



Setup Schedule
Set up: Mon-Thurs p.m.; Report available: Next day


Report Available

Next day



Reference Range
≤5 Months 5.0-10.0 mg/L
>5 Months 10.0-20.0 mg/L


Clinical Significance
Theophylline is used in the treatment of bronchial asthma as well as in the treatment of chronic obstructive pulmonary disease and episodes of prolonged apnea in pre-term infants. Theophylline levels are monitored to assure adequate therapeutic levels are achieved and to avoid toxicity.


Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153


Last Updated: February 20, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.