| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
TSH with HAMA Treatment
Test CodeTSHHM
Alias/See Also
LAB11916
CPT Codes
<p>84443 (x2)</p>
Includes
Ultrasensitive TSH with and without HAMA treatment
Preferred Specimen
Patient Preparation: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay. "
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Patient Preparation
Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra Assay."
Minimum Volume
1.5 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 2-3 days
Report Available
2-3 days
Reference Range
| TSH, HAMA Treated | See below |
| TSH, Untreated | |
| Premature infant (28-36 weeks), 1st week of life | 0.20-27.90 mIU/L |
| Term infant (>37 Weeks), serum or cord blood | 1.00-39.00 mIU/L |
| 1-2 Days | 3.20-34.60 mIU/L |
| 3-4 Days | 0.7-15.40 mIU/L |
| 5 Days-4 Weeks | 1.70-9.10 mIU/L |
| 1-11 Months | 0.80-8.20 mIU/L |
| 1-19 Years | 0.50-4.30 mIU/L |
| ≥20 Years | 0.40-4.50 mIU/L |
| Pregnancy | |
| First Trimester | 0.26-2.66 mIU/L |
| Second Trimester | 0.55-2.73 mIU/L |
| Third Trimester | 0.43-2.91 mIU/L |
Clinical Significance
Precision in the estimation of TSH is crucial to the follow-up of subjects with thyroid disorders. The preincubation of samples to remove HAMA immunoglobulins provides a way to ensure that an otherwise unsuspected rise or drop in TSH concentration will not be interpreted as either a false positive or false negative.
Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675
Last Updated: February 17, 2023