Levetiracetam, Immunoassay

Test Code

LEVE

Alias/See Also

LAB477

CPT Codes
<p>80177</p>

Preferred Specimen

Patient Preparation: If Brivaracetam has been prescribed, order send out test for Levetiracetam by GC/MS.

Optimum Time to Collect Sample:

0.5 to 1 hour pre-oral dose, trough at steady state (2 weeks after onset of treatment).

Specimen Type: Serum

Collection Container/Type: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Specimen Type: Plasma

Collection Container/Type

Preferred: Lavender top (EDTA)

Acceptable: Green top (lithium or sodium heparin)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Patient Preparation

If Brivaracetam has been prescribed, order test code 15142 for Levetiracetam by LCMSMS.

Optimum Time to Collect Sample: 0.5 to 1 hour pre-oral dose, trough at steady state (2 weeks after onset of treatment).

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days

Refrigerated: 21 days

Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Specimens collected in any gel barrier tubes • Unspun red-top tube (no-gel)

Methodology

Immunoassay (IA)

Setup Schedule

Monday-Saturday Morning
Report available: 2 Days

Report Available

2-3 days

Reference Range

6.0-46.0 mcg/mL

Clinical Significance

LEV is currently used as an anti-epileptic drug for the treatment of adult partial seizures particularly as an add-on therapy for refractory patients. It also has potential for other anxiety and cognitive disturbances.

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: February 17, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.