Lactic Acid, CSF

Test Code
LACSF


Alias/See Also

LAB187



CPT Codes
<p>83605</p>

Preferred Specimen

Specimen Type: CSF


Collection Container/TypeSterile container


Submission Container/Tube: Sterile container


Specimen Volume: 1 mL


Collection Instructions: If specimen is not clear or contains blood, centrifuge and separate supernatant fluid before freezing.


Additional Information:



  • The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for lactate (lactic acid), leading to falsely low results.



Minimum Volume

0.5 mL



Instructions
If specimen is not clear or contains blood, centrifuge and separate supernatant fluid before freezing.

Note:
The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for lactate (lactic acid), leading to falsely low results.


Transport Temperature
Frozen


Specimen Stability

Room temperature: 3 hours


Refrigerated: 24 hours


Frozen: 90 days



Methodology

Spectrophotometric



Setup Schedule
Monday-Friday All Shifts Sunday Night Report available: Next Day


Report Available

1-2 days



Reference Range
Neonate 10-60 mg/dL
3-10 Days 10-40 mg/dL
11 Days-15 Years 10-25 mg/dL
Adult 10-22 mg/dL


Clinical Significance
Lactic Acid levels in CSF normally parallel blood levels. Increased CSF Lactic Acid levels occur in trauma, seizure, brain abscess, Multiple Sclerosis, and bacterial meningitis.


Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153


Last Updated: February 17, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.