ThinPrep® Pap with Reflex to HPV mRNA E6/E7

Message

Effective 11/09/2023: Test will be obsolete.
Testing is being replaced with Imaging Pap and HPV mRNA test codes. The recommended replacement codes are listed below.
TPRHI [LAB13988] ThinPrep Pap w/ Image Analysis reflex to HPV

Test Code

TPHPL

Alias/See Also

Epic: LAB13044

CPT Codes
88142<br><strong>This test is not available for California patient testing.</strong>

Includes

Pap results requiring physician interpretation will be performed at an additional charge (CPT Code(s): 88141; HCPCS: G0124).
If ThinPrep® Pap result is ASCUS, then HPV mRNA E6/E7 will be performed at an additional charge (CPT Code(s): 87624).

Preferred Specimen

Pap sample collected in 1 ThinPrep® pap vial

Minimum Volume

1 ThinPrep vial

Instructions

For instructions refer to
//www.questdiagnostics.com/dms/Documents/Other/Specimen_Collection_and_Transport_Guide_2019.pdf

Transport Temperature

Room temperature

Specimen Stability

Pap
Room temperature: 42 days
Refrigerated: Unacceptable
Frozen: Unacceptable

HPV - ThinPrep Pap vial
Room temperature: 30 days
Refrigerated: 105 days
Frozen: Unacceptable

ThinPrep in Aptima® transfer tube
Room temperature: 60 days
Refrigerated: 60 days
Frozen: 24 months

Refer to local service area for specimen retention

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

ThinPrep pap vials received refrigerated or frozen • Swabs • Cervical swabs in Digene® HC cervical sampler • Digene® vials

Methodology
Hologic ThinPrep® System

Reflex: Transcription-Mediated Amplification (TMA)

Setup Schedule

Set up: Mon-Sat; Report available: 10 days

Reference Range

See Laboratory Report

Clinical Significance

Liquid based pap testing is intended for use in the screening and detection of cervical cancer, pre-cancerous lesions, atypical cells and all other cytologic categories as defined by the Bethesda System for reporting results of cervical cytology. Pap screening is not reliable for the detection of endometrial cancer.

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: November 1, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.