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Deoxycorticosterone, LC/MS/MS
MessageSpin down immediately and pour off into a plastic screw-cap
vial
Test Code
DEOXY
Alias/See Also
LAB974
CPT Codes
82633
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.25 mL
Instructions
Spin down immediately and pour off into a plastic transport tube.
Transport Container
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
Room temperature: 72 hours Refrigerated: 7 days Frozen: 30
days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Moderate hemolysis • Gross hemolysis • Gross lipemia
• Gross icterus • Serum Separator Tube (SST ®)
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Tues, Sun nights
Report Available
5-10 days
Reference Range
Male ≥18 Years ≤15 ng/dL
Female-Phase of Menstrual Cycle
Mid Follicular ≤18 ng/dL
Surge ≤23 ng/dL
Mid Luteal ≤19 ng/dL
Pediatric 16-17 Years ≤35 ng/dL
Clinical Significance
Deoxycorticosterone (DOC) is a weak mineralocorticoid derived from 21-hydroxylation of progesterone in the adrenal cortex. DOC is a precursor of corticosterone and aldosterone and, like cortisol, is under the primary control of ACTH.
Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano 33608 Ortega Highway San Juan Capistrano, CA 92675
Last Updated: February 17, 2023