Deoxycorticosterone, LC/MS/MS

Message

Spin down immediately and pour off into a plastic screw-cap
vial



Test Code
DEOXY


Alias/See Also

LAB974



CPT Codes
82633

Preferred Specimen

0.5 mL serum collected in a red-top tube (no gel)



Minimum Volume

0.25 mL



Instructions
Spin down immediately and pour off into a plastic transport tube.


Transport Container
Plastic screw-cap vial


Transport Temperature

Frozen



Specimen Stability

Room temperature: 72 hours Refrigerated: 7 days Frozen: 30
days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Moderate hemolysis • Gross hemolysis • Gross lipemia
• Gross icterus • Serum Separator Tube (SST ®)



Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)



Setup Schedule

Tues, Sun nights



Report Available

5-10 days



Reference Range

Male ≥18 Years ≤15 ng/dL



Female-Phase of Menstrual Cycle  

  Mid Follicular ≤18 ng/dL

  Surge ≤23 ng/dL

  Mid Luteal ≤19 ng/dL



Pediatric 16-17 Years ≤35 ng/dL



Clinical Significance
Deoxycorticosterone (DOC) is a weak mineralocorticoid derived from 21-hydroxylation of progesterone in the adrenal cortex. DOC is a precursor of corticosterone and aldosterone and, like cortisol, is under the primary control of ACTH.


Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano 33608 Ortega Highway San Juan Capistrano, CA 92675


Last Updated: February 17, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.