| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Mumps Virus Antibody, IgG
Test CodeMUMGG
Alias/See Also
Epic: LAB160
Preferred Specimen
Specimen Type: Serum
Collection Container: Serum gel
Specimen Volume: 3 mL
Minimum Volume
0.5 mL
Other Acceptable Specimens
Collection Container: Red top
Instructions
Centrifuge and separate cells after clot formation and within 4 hours of collection.
Transport Container
Plastic vial
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 9 days
Frozen: >9 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Unlabeled, mislabeled, wrong tube type, QNS, severely hemolyzed samples and any sample from which the lipid layer has not been removed.
Setup Schedule
Daily
Report Available
1 day
Reference Range
≥ 11.0
A positive result indicates exposure to mumps virus or previous vaccination and provides presumptive evidence of immunity.
A positive result indicates exposure to mumps virus or previous vaccination and provides presumptive evidence of immunity.
Clinical Significance
Mumps is a viral illness caused by a member of the paramyxovirus family and is transmitted by respiratory droplets. It has an incubation period of 14-25 days after which time prodromal symptoms occur and last anywhere from three to five days. After the prodromes, the symptoms of the viral infection depend on which organ is affected. The most common presentation is a parotitis, which occurs in 30-40% of patients. Other reported sites of infection are the testes, pancreas, eyes, ovaries, central nervous system, joints, and kidneys. A patient is considered infectious from about three days before the onset of symptoms and up to four days after the start of active parotitis. Infections can be asymptomatic in up to 20% of persons.
Prior to vaccine availability about 50% of children contracted mumps; however mumps vaccination programs (part of measles, mumps, rubella, varicella [MMRV] vaccination) have had a marked effect on the incidence of the disease and the complications associated with it.
When mumps was a common disease of childhood, the diagnosis was established largely on clinical grounds alone. With the decreased incidence of mumps, many physicians no longer readily recognize the symptoms. In addition, typical clinical signs and symptoms may be absent in underimmunized or immunocompromised individuals; approximately 20 to 30% of infections are sub-clinical. Parotitis, the hallmark of clinical diagnosis, is also now known to be present in other viral and non-viral diseases or conditions. Mumps-like symptoms in acutely ill children who previously received the MMRV vaccine have been associated with Epstein-Barr virus, human parainfluenza viruses (HPIV), adenovirus, and human herpesvirus type 6. Therefore laboratory confirmation of mumps virus infection is now more important in establishing the diagnosis.
Prior to vaccine availability about 50% of children contracted mumps; however mumps vaccination programs (part of measles, mumps, rubella, varicella [MMRV] vaccination) have had a marked effect on the incidence of the disease and the complications associated with it.
When mumps was a common disease of childhood, the diagnosis was established largely on clinical grounds alone. With the decreased incidence of mumps, many physicians no longer readily recognize the symptoms. In addition, typical clinical signs and symptoms may be absent in underimmunized or immunocompromised individuals; approximately 20 to 30% of infections are sub-clinical. Parotitis, the hallmark of clinical diagnosis, is also now known to be present in other viral and non-viral diseases or conditions. Mumps-like symptoms in acutely ill children who previously received the MMRV vaccine have been associated with Epstein-Barr virus, human parainfluenza viruses (HPIV), adenovirus, and human herpesvirus type 6. Therefore laboratory confirmation of mumps virus infection is now more important in establishing the diagnosis.
Performing Laboratory
Inova Laboratories
2832 Juniper Street
Fairfax, VA 22031
Last Updated: April 11, 2023
Last Review: N. Wolford, April 11, 2023