Tobramycin, Trough

Test Code

TOBRT

Alias/See Also

Epic: LAB38

Preferred Specimen

Specimen Type: Serum
Collection Container: Serum gel
Specimen Volume: 3 mL

Minimum Volume

0.25 mL

Other Acceptable Specimens

Collection Container: Red top

Instructions

Draw blood no more than 30 minutes before next scheduled dose
Centrifuge and separate cells after clot formation and within 4 hours of collection.

Transport Container

Plastic vial

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Unlabeled, mislabeled, wrong tube type, hemolyzed, visually lipemic, QNS, exceeds specimen/stability requirements.

Methodology

Particle-enhanced turbidimetric inhibition immunoassay (PETINIA).

Setup Schedule

Daily

Report Available

Same day

Reference Range

Therapeutic: 0.2 – 2.0 µg/mL

Clinical Significance

The MULTIGENT Tobramycin assay is intended for the quantitative determination of tobramycin in human serum.

Tobramycin sulfate is an aminoglycoside antibiotic used to treat serious bacterial infections by intervening in the bacterial protein synthesis thereby killing the bacterium. Therapeutic serum levels vary depending on the microorganism involved and the patient's tolerance to the drug. The average half-life in patients with normal renal function is about 2-3 hours.

Monitoring serum levels of tobramycin decreases the frequency of serious toxic effects.

Performing Laboratory

Inova Laboratories

2832 Juniper Street

Fairfax, VA 22031

Last Updated: April 17, 2023
Last Review: N. Wolford, April 17, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.