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Intrinsic Factor Blocking Antibody
Test CodeIFBA
Alias/See Also
LAB857
CPT Codes
<p>86340</p>
Preferred Specimen
Patient Preparation: Samples should not be collected from a patient who has received vitamin B12 injection therapy within the past week.
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Minimum Volume
0.3 mL
Instructions
Samples should not be collected from a patient who has received vitamin B12 injection therapy within the past week.
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-2 days
Report Available
1-2 days
Reference Range
Negative
Clinical Significance
Intrinsic Factor, produced by cells lining the stomach, binds Vitamin B12 (cyanocobalamin) to facilitate absorption of the vitamin. Blocking antibody impedes the action of Intrinsic Factor as observed in approximately half of the patients who develop pernicious anemia.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 23, 2012