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Mitochondrial Antibody Screen with Reflex to Titer
Test CodeMARTP
CPT Codes
86381
Includes
If Mitochondrial Antibody Screen is positive, then Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86381).
Preferred Specimen
0.5 mL serum
Minimum Volume
0.1 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days Refrigerated: 14 days Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Fri a.m.; Report available: Next day
Reference Range
Negative
Clinical Significance
A high Anti-Mitochondrial Antibody (AMA) titer supports the diagnosis of primary biliary cirrhosis (PBC). Low titers of AMA may be detected in other liver disorders, which include chronic active hepatitis and cryptogenic cirrhosis. Mitochondrial M2 Antibody has an even higher specificity for PBC.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 23, 2012