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JC Polyoma Virus DNA, Qualitative Real-Time PCR, CSF
Test CodeJCPCR
Alias/See Also
LAB12513
CPT Codes
<p>87798</p>
Preferred Specimen
Specimen Type: CSF
Collection Container/Type: Sterile container
Submission Container/Tube: Sterile container
Specimen Volume: 0.7 mL
Minimum Volume
0.3 mL
Instructions
Transport Temperature
Frozen
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Methodology
Real-Time Polymerase Chain Reaction
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily a.m.; Report available: 1 day
Report Available
1 day
Reference Range
Not detected
Clinical Significance
JC Polyoma Virus (JCV) is the cause of progressive multi- focal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC polyoma virus DNA in CSF. Detection of the virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.
Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153
Last Updated: February 1, 2012