Kappa/Lambda Light Chains, Free with Ratio Reflex to Immunofixation, Serum

Test Code

KLLCF

CPT Codes
<p>83521 (x2)</p>

Includes

If Kappa/Lambda, Free is <0.26 or >1.65, then Immunofixation, Serum will be performed at an additional charge (CPT code(s): 86334).

Preferred Specimen

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Minimum Volume

1 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours

Refrigerated: 7 days

Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Microbially contaminated serum • Specimens containing heavy visible particulate

Methodology

Immunoturbidimetric

Setup Schedule

Set up: Mon-Fri; Report available: 2-7 days

Report Available

2-7 days

Reference Range

Kappa Light Chain, Free, Serum	3.3-19.4 mg/L
Lambda Light Chain, Free, Serum	5.7-26.3 mg/L
Kappa/Lambda Light Chains Free with Ratio, Serum	0.26-1.65

Clinical Significance

Measurement of the amounts of the different light chain types aids in the diagnosis and monitoring of multiple myeloma, lymphocytic neoplasms, Waldenstrom's macroglobulinemia, and connective tissue diseases, such as systemic lupus erythematosus.

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: February 23, 2012

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.