Tissue Transglutaminase (tTG) Antibodies (IgG, IgA)

Test Code

TTAP

Alias/See Also

LAB3391

CPT Codes
<p>86364 (x2)</p>

Preferred Specimen

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Minimum Volume

0.5 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days

Refrigerated: 14 days

Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology

Immunoassay (IA)

Setup Schedule

Set up: Tues-Sat; Report available: Next day

Report Available

Next day

Reference Range

Tissue Transglutaminase Antibody, IgG

<15.0 U/mL	Antibody not detected
≥15.0 U/mL	Antibody detected

Tissue Transglutaminase Antibody, IgA

<15.0 U/mL	Antibody not detected
≥15.0 U/mL	Antibody detected

Clinical Significance

Tissue Transglutaminase Antibody, IgA, is useful in diagnosing gluten-sensitive enteropathies, such as Celiac Sprue Disease, and an associated skin condition, dermatitis herpetiformis. The IgG test is useful in patients who are IgA-deficient. The IgG test also provides support for gluten-sensitive enteropathies beyond the IgA test.

Performing Laboratory
Quest Diagnostics Nichols Institute 14225 Newbrook Drive Chantilly, VA 20153

Last Updated: February 24, 2012

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.