Hepatitis B Surface Antibody, Quant

Message

Chemistry

Test Code

LAB5210185

Alias/See Also

aHBs

Preferred Specimen

Gold top (serum separator tube)

Minimum Volume

Whole blood: 800 uL (TWO full red-top microtainers).

Serum/plasma: 400 uL

Other Acceptable Specimens

Red Top tube acceptable

Specimen Stability

Room Temperature: 8 hours
Refrigerated: up to 48 hours
Frozen: indefinite

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly Lipemic, Grossly Hemolyzed
Plasma specimens.

Setup Schedule

Everyday

Limitations

Test performance characteristics have not been established when the Anti-HBs Quantitative test is used in conjunction with other manufacturer’s tests for specific HBV serological markers.
Test performance characteristics have not been established for the use of the Anti-HBs Quantitative test as an aid in determining susceptibility to HBV infection prior to or following vaccination in infants, children, or adolescents.
The results from this or any other diagnostic test should be used and interpreted only in the context of the overall clinical picture.
This test does not differentiate between a vaccine induced immune response and an immune response induced by infection with HBV. To determine if the anti-HBs response is due to vaccine or HBV infection, a total anti-HBc test may be performed.
Individuals that have received blood component therapy, e.g., whole blood, plasma, immune globulin administration, during the previous 3–6 months may have a false reactive anti-HBs result due to passive transfer of anti-HBs.

Reference Range

Anti-HBs Test Result	Result Text	Clinical Interpretation of Immune Status
<5.00 mIU/mL	Negative	Patient is considered to be not immune to infection with HBV.
≥5.00 mIU/mL and <12.0 mIU/mL	Indeterminate	Unable to determine if anti-HBs is present at levels consistent with immunity. Patient's immune status should be further assessed by considering other clinical information or retesting another specimen drawn at a later time.
≥12.0 mIU/mL	Positive	Patient is considered to be immune to infection with HBV. It has not been determined what the clinical significance is for values greater than ≥12 mIU/mL, other than the individual is considered to be immune to HBV infection.

Clinical Significance

The clinical significance of quantitative values reported ≥12.0 mIU/mL has not been determined, other than the individual is presumed to be immune to HBV infection. The clinical significance of quantitative values reported ≥4.23 mIU/mL and <5.00 mIU/mL has not been determined, other than the individual is considered to be not immune to HBV infection.

Performing Laboratory
Hoag Newport

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.