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C-Reactive Protein, High Sensitivity
MessageChemistry
Test Code
LAB150
Alias/See Also
hsCRP
CPT Codes
86141
Preferred Specimen
Gold top (serum separator tube)
Minimum Volume
Whole blood: 600 uL (TWO full red-top microtainers or one full light green-top microtainer).
Serum/plasma: 300 uL
Serum/plasma: 300 uL
Other Acceptable Specimens
Red Top and light green top (lithium heparin plasma) acceptable
Instructions
LAB: Centrifuge specimens and remove the serum from the cellular material within two hours of collection.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: ≤4 hours
Refrigerated: ≤ 3 days
Frozen: ≤ 6 months
Refrigerated: ≤ 3 days
Frozen: ≤ 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed specimens
Methodology
Turbidimetric
Setup Schedule
Everyday
Report Available
Within 8 hours
Reference Range
≤17 years: Not established
>17 years: Optimal <1.0 mg/L
hsCRP level (mg/L) Risk According to AHA/CDC Guidelines
<1.0 Lower Relative Cardiovascular Risk
1.0-3.0 Average Relative Cardiovascular Risk
>3.0-10.0 Higher Relative Cardiovascular Risk. Consider retesting in 1 to 2 weeks to exclude a benign transient
elevation on the baseline CRP value secondary to infection or inflammation.
>10.0 Persistent elevations upon retesting, may be associated with infection or inflammation
>17 years: Optimal <1.0 mg/L
hsCRP level (mg/L) Risk According to AHA/CDC Guidelines
<1.0 Lower Relative Cardiovascular Risk
1.0-3.0 Average Relative Cardiovascular Risk
>3.0-10.0 Higher Relative Cardiovascular Risk. Consider retesting in 1 to 2 weeks to exclude a benign transient
elevation on the baseline CRP value secondary to infection or inflammation.
>10.0 Persistent elevations upon retesting, may be associated with infection or inflammation
Performing Laboratory
Hoag Newport