Centromere B Antibody

Test Code
LAB5210390


Quest Code
16088


CPT Codes
86235

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Temperature
Room temperature


Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Immunoassay (IA)

Setup Schedule
P.M. Sets up 6 days a week.


Limitations
As many as 15% of health controls may have low or slightly elevated antibody levels.


Reference Range
<1.0 AI Negative


Clinical Significance
Centromere B Antibody is diagnostic for the form of scleroderma known as CREST (calcinosis, Raynaud's phenomenon, esophageal immotility, sclerodactyly, and telangiectasia).


Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.