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Centromere Antibody, IgG
MessageSendout, Mayo test code:CMA
Test Code
LAB5210456
Alias/See Also
ACA (Anticentromere Antibodies)
Anticentromere Antibodies Centromere Antibodies
IgG Centromere Autoantibodies CREST HEp-2 Scleroderma Antibodies
Centromere Antibody Anti-Centromere Antibodies
CMA
Anticentromere Antibodies Centromere Antibodies
IgG Centromere Autoantibodies CREST HEp-2 Scleroderma Antibodies
Centromere Antibody Anti-Centromere Antibodies
CMA
CPT Codes
83516
Preferred Specimen
10.5 mL serum from a gold serum gel tube
Minimum Volume
0.35 mL
Other Acceptable Specimens
Red tube
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated (preferred): 21 days
Frozen: 21 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis Mild OK; Gross reject Lipemia Mild OK; Gross reject Icterus Mild OK; Gross OK Other NA
Methodology
Multiplex Flow Immunoassay
FDA Status
Approved
Setup Schedule
Monday through Saturday
Report Available
1-3 days
Limitations
Centromere antibodies have also been described in some patients with primary biliary cirrhosis, and may occur in patients with rheumatoid arthritis or lupus erythematosus.
Reference Range
Included with report
Clinical Significance
Evaluating patients with clinical signs and symptoms compatible with systemic sclerosis including skin involvement, Raynaud phenomenon, and arthralgias.
Aiding in the diagnosis of calcinosis, Raynaud phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasis (CREST) syndrome.
Aiding in the diagnosis of calcinosis, Raynaud phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasis (CREST) syndrome.
Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota
Additional Information
Centromere Antibodies, IgG, Serum
