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Tacrolimus Level
MessageSendout, UCI test code: FK506
Test Code
LAB876
Alias/See Also
FK506
Prograf
Prograf
CPT Codes
80197
Preferred Specimen
3 ml. whole blood in a lavender EDTA tube. DO NOT SHARE TUBE WITH OTHER TESTS.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Pink EDTA tube
Instructions
Specimen must arrive at UCI within 72 hours of draw.
Transport Container
Original container
Transport Temperature
Ambient
Specimen Stability
Ambient: 72 hours
Refrigerated: 7 days
Frozen: 14 days
Refrigerated: 7 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens that exceed stated stability, unlabeled/mislabeled/mismatched specimens, specimens submitted in leaking containers
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LCMS/MS
FDA Status
Approved
Setup Schedule
Daily. Cutoff time is 12:00 noon.
Report Available
4 - 6 hours upon receipt at UCI
Reference Range
Included with report
Clinical Significance
Collecting sample just before the next dose will be adequate for monitoring purposes. Optimal response to tacrolimus is usually associated with the trough blood concentration (i.e., the minimum concentration experienced just before the next dose).
Performing Laboratory
UCI Medical Center, Orange, California
Additional Information
Tacrolimus