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Estrone
MessageSendout, Mayo test code: E1
Test Code
LAB982
Alias/See Also
E1 (Estrone)
Estrone (E1), Serum
Estrone (E1), Serum
CPT Codes
82679
Preferred Specimen
1.2 mL serum from a red tube. SERUM GEL TUBE IS UNACCEPTABLE.
Minimum Volume
0.8 mL
Instructions
1. Centrifuge and remove serum from red blood cells within 2 hours of draw.
2. Aliquot serum to submission container.
2. Aliquot serum to submission container.
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated (preferred): 28 days
Ambient: 28 days
Frozen: 28 days
Ambient: 28 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis: Mild OK; Gross OK
Lipemia: Mild OK; Gross OK
Icterus: Mild OK; Gross OK
Other: Serum gel or SST tube
Lipemia: Mild OK; Gross OK
Icterus: Mild OK; Gross OK
Other: Serum gel or SST tube
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
FDA Status
Approved
Setup Schedule
Monday through Saturday
Report Available
2-6 days
Reference Range
Included with report
Clinical Significance
As part of the diagnosis and workup of precocious and delayed puberty in females and, to a lesser degree, males.
As part of the diagnosis and workup of suspected disorders of sex steroid metabolism (eg, aromatase deficiency and 17 alpha-hydroxylase deficiency).
As an adjunct to clinical assessment, imaging studies and bone mineral density measurement in the fracture risk assessment of postmenopausal women, and, to a lesser degree, older men.
Monitoring low-dose female hormone replacement therapy in postmenopausal women.
Monitoring antiestrogen therapy (eg, aromatase inhibitor therapy).
As part of the diagnosis and workup of suspected disorders of sex steroid metabolism (eg, aromatase deficiency and 17 alpha-hydroxylase deficiency).
As an adjunct to clinical assessment, imaging studies and bone mineral density measurement in the fracture risk assessment of postmenopausal women, and, to a lesser degree, older men.
Monitoring low-dose female hormone replacement therapy in postmenopausal women.
Monitoring antiestrogen therapy (eg, aromatase inhibitor therapy).
Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota
Additional Information
Estrone, Serum
