| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Tryptase
MessageSendout, Mayo test code: TRYPT
Test Code
LAB827
Alias/See Also
Mast Cell Tryptase
TRYPT
TRYPT
CPT Codes
83520
Preferred Specimen
0.5 mL serum from a gold serum gel tube
Minimum Volume
0.2 mL
Other Acceptable Specimens
Red tube
Instructions
Centrifuge and aliquot serum into plastic vial.
Additional Information: Tryptase degenerates very quickly when left in the presence of red blood cells.
Additional Information: Tryptase degenerates very quickly when left in the presence of red blood cells.
Transport Container
Plastic vial
Transport Temperature
Frozen
Specimen Stability
Frozen (preferred): 14 days
Refrigerated: 7 days
Refrigerated: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis: OK
Gross lipemia: OK
Gross icterus: OK
Gross lipemia: OK
Gross icterus: OK
Methodology
Fluorescence Enzyme Immunoassay (FEIA)
FDA Status
Approved
Setup Schedule
Monday through Friday
Report Available
2-5 days
Limitations
Normal tryptase concentrations may be observed in some patients with acute mast cell activation if specimens are obtained greater than 12 hours after an anaphylactic episode or allergen challenge.
Some individuals may demonstrate an increase in tryptase concentrations above baseline after anaphylaxis or allergen challenge while remaining below 11.5 ng/mL; measurement of tryptase in specimens obtained 1 to 6 hours and at least 24 hours after the episode may be useful in demonstrating a transient increase in concentrations.
Some individuals may demonstrate an increase in tryptase concentrations above baseline after anaphylaxis or allergen challenge while remaining below 11.5 ng/mL; measurement of tryptase in specimens obtained 1 to 6 hours and at least 24 hours after the episode may be useful in demonstrating a transient increase in concentrations.
Reference Range
Included with report
Clinical Significance
Evaluation of individuals with suspected mast cell activation, which may occur as a result of anaphylaxis or allergen challenge
Evaluation of patients with suspected cutaneous or systemic mastocytosis
Evaluation of patients with suspected cutaneous or systemic mastocytosis
Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota
Additional Information
Tryptase, Serum
