Endomysial Ab, IgA

Message

Sendout, Mayo test code: EMA

Test Code

LAB774

Alias/See Also

Anti-Endomysial Antibody
Antiendomysial Antibody
Antimesothelial Antibody
Celiac Disease
Coeliac Disease
Cutaneous Immunofluorescence
Dermatitis herpetiformis D
ermatoimmunopathology
EA
EMA
Failure to Thrive
Gluten-sensitive
Enteropathy IgA Antibodies
EMA

CPT Codes
86231, 86231-tier (if appropriate)

Preferred Specimen

2 mL serum from a gold serum gel tube

Minimum Volume

0.5 mL

Other Acceptable Specimens

Red tube

Instructions

Centrifuge and aliquot serum into a plastic vial.

Transport Container

Plastic vial

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated (preferred): 14 days
Frozen: 30 days
Ambient: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis: Mild OK; Gross reject
Lipemia: Mild reject; Gross reject
Icterus: Mild OK; Gross reject

Methodology
Staining of Rhesus Monkey Esophagus Substrate by Indirect Immunofluorescence Assay (IFA) for IgA Endomysial Antibodies (EMA)

FDA Status
Approved

Setup Schedule

Monday through Friday

Report Available

2-7 days

Limitations

Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen-dependent. Best practice is for paraffin sections to be cut within 6 weeks.

Reference Range

Included with report

Clinical Significance

Analysis of IgA-endomysial antibodies for the diagnosis of dermatitis herpetiformis and celiac disease.
Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease.

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
Endomysial Antibodies, IgA, Serum

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.