Zonisamide Level

Message

Sendout, Mayo test code: ZONI

Test Code

LAB504

Alias/See Also

Zonisamide (Zonegran)
ZONI

CPT Codes
80203

Preferred Specimen

1 mL serum from a red tube. SERUM GEL TUBE IS UNACCEPTABLE.

Minimum Volume

0.5 mL

Instructions

Centrifuge and aliquot serum into plastic vial within 2 hours of collection.

Transport Container

Plastic vial

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated (preferred): 28 days
Ambient: 28 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis: Mild OK; Gross OK
Lipemia: Mild OK; Gross OK
Icterus: Mild OK; Gross OK
Other Serum Gel, SST

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

FDA Status
Approved

Setup Schedule

Monday through Saturday

Report Available

1-5 days

Limitations

Rufinamide is a known interference of this assay. Patients who are coadministered zonisamide and rufinamide may have falsely elevated and uninterpretable zonisamide concentrations reported by this assay.

Reference Range

Included with report

Clinical Significance

Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing

Assessing medication compliance

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
Zonisamide, Serum

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.