Oxcarbazepine Metabolite Level

Message

Sendout, Mayo test code: OMHC

Test Code

LAB484

Alias/See Also

10-Hydroxy-10,11-Dihydrocarbamazepine (Metabolite of Oxcarbazepine)
10-Hydroxycarbazepine
MHC (Oxcarbazepine Metabolite)
MHD (Oxcarbazepine Metabolite)
Monohydroxy Carbamazepine
Oxcarbazepine Metabolite (MHC)
Trileptal (Oxcarbazepine)
OMHC

CPT Codes
80183

Preferred Specimen

1 mL serum collected in a red tube. Serum separator tube (SST) is not acceptable.

Minimum Volume

0.5 mL

Instructions

1. Collect specimen immediately before next scheduled dose.
2. Centrifuge and aliquot serum into plastic vial within 2 hours of collection.

Transport Container

Plastic vial

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated (preferred): 28 days
Ambient: 28 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis: OK
Gross lipemia: OK
Gross icterus: OK
Serum Separator Tube (SST)

Methodology
High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)

FDA Status
Approved

Setup Schedule

Monday through Saturday

Report Available

1-3 days

Limitations

Toxic levels have not been well established.

This test cannot be performed on whole blood. Serum must be separated from cells within 2 hours of collection.

Reference Range

Included with report

Clinical Significance

Monitoring serum concentration during oxcarbazepine therapy

Assessing compliance

Assessing potential toxicity

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
Oxcarbazepine Metabolite, Serum

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.