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Lamotrigine Level
MessageSendout, Mayo test code: LAMO
Test Code
LAB475
Alias/See Also
Lamictal
LAMO
LAMO
CPT Codes
80175
Preferred Specimen
1 mL serum from a red tube
Minimum Volume
0.5 mL
Other Acceptable Specimens
Serum gel tube
Instructions
1. Draw blood immediately before next scheduled dose.
2. For sustained-release formulations only, draw blood a minimum of 12 hours after last dose.
3. Centrifuge within 2 hours of collection
4. For red-top tubes, immediately aliquot serum into a plastic vial.
5. For serum gel tubes, aliquot serum into a plastic vial within 24 hours of collection.
2. For sustained-release formulations only, draw blood a minimum of 12 hours after last dose.
3. Centrifuge within 2 hours of collection
4. For red-top tubes, immediately aliquot serum into a plastic vial.
5. For serum gel tubes, aliquot serum into a plastic vial within 24 hours of collection.
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated (preferred): 28 days
Room temperature: 48 hours
Frozen: 28 days
Room temperature: 48 hours
Frozen: 28 days
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
FDA Status
Approved
Setup Schedule
Monday through Saturday
Report Available
1-2 days
Limitations
Serum separator tube is acceptable but serum should be removed from gel within 24 hours of collection.
Reference Range
Included with report
Clinical Significance
Monitoring serum concentration of lamotrigine
Assessing compliance
Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine
Assessing compliance
Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine
Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota
Additional Information
Lamotrigine, Serum
