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Mumps Virus Antibody, IgG and IgM
MessageSendout, Mayo test directory: MMPGM
Test Code
LAB5210319
Alias/See Also
Mumps Serology
Mumps Antibody
MMPGM
Mumps Antibody
MMPGM
CPT Codes
86735x2
Preferred Specimen
1 mL serum from a gold serum gel tube
Minimum Volume
0.9 mL serum
Other Acceptable Specimens
Red tube
Instructions
Centrifuge and aliquot serum into plastic vial.
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated (preferred): 14 days
Frozen: 14 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis: Reject
Gross lipemia: Reject
Heat-inactivated specimen: Reject
Gross lipemia: Reject
Heat-inactivated specimen: Reject
Methodology
MMPM: Enzyme Immunoassay (EIA)
MPPG: Multiplex Flow Immunoassay (MFI)
FDA Status
Approved
Setup Schedule
MMPM: Tuesday
MPPG: Monday through Saturday
MPPG: Monday through Saturday
Report Available
1-7 days
Limitations
Serum specimens obtained during the acute phase of infection or soon after vaccination may be negative for IgM- or IgG-class antibodies by serological tests.
All positive IgM results must be interpreted cautiously as some false-positive results or heterotypical responses of the IgM have been seen in the serum of pregnant women or in patients with an acute infection caused by cytomegalovirus, herpes simplex virus, measles, rubella, or parvovirus.
Testing for IgM-class antibodies to mumps virus should be limited to patients with a clinically compatible disease.
Mumps virus shares antigenic relationships with other viruses of the paramyxovirus group; therefore, serologic cross-reactions are possible, but uncommon, with this test procedure.
IgG-class antibodies to mumps virus may be present in serum specimens from individuals who have received blood products within the past several months but have not been immunized or experienced past infection with this virus.
All positive IgM results must be interpreted cautiously as some false-positive results or heterotypical responses of the IgM have been seen in the serum of pregnant women or in patients with an acute infection caused by cytomegalovirus, herpes simplex virus, measles, rubella, or parvovirus.
Testing for IgM-class antibodies to mumps virus should be limited to patients with a clinically compatible disease.
Mumps virus shares antigenic relationships with other viruses of the paramyxovirus group; therefore, serologic cross-reactions are possible, but uncommon, with this test procedure.
IgG-class antibodies to mumps virus may be present in serum specimens from individuals who have received blood products within the past several months but have not been immunized or experienced past infection with this virus.
Reference Range
Included with report
Clinical Significance
Diagnosis of mumps virus infection
Determination of postimmunization immune response of individuals to the mumps vaccine
Documentation of previous infection with mumps virus in an individual with no previous record of immunization to mumps virus
Determination of postimmunization immune response of individuals to the mumps vaccine
Documentation of previous infection with mumps virus in an individual with no previous record of immunization to mumps virus
Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota
Additional Information
Mumps Virus Antibody, IgM and IgG, Serum
