Epstein-Barr Virus Early Antigen Ab, IgG

Message

Sendout, Mayo test code: EAEBV

Test Code

LAB654

Alias/See Also

EBV IgG Antibody to Early Antigen
E. B. Virus (Early Antigen)
EA (Early Antigen)
Early Antigen EBV EARLY AG(S)
Epstein Barr Virus Early Ag Ab
Epstein-Barr Virus (EBV) Early Antigen
EBVE
EAEBV

CPT Codes
86663

Preferred Specimen

1 mL serum from a gold serum gel tube

Minimum Volume

0.4 mL

Other Acceptable Specimens

Red tube

Instructions

Centrifuge and aliquot serum into a plastic vial.

Transport Container

Plastic vial

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated (preferred): 14 days
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis: Reject
Gross lipemia: Reject
Heat-activated specimen: Reject

Methodology
Enzyme-Linked Immunosorbent Assay (ELISA)

FDA Status
Approved

Setup Schedule

Monday through Friday

Report Available

1-3 days

Limitations

This test detects both restricted (R) and diffuse (D) forms the Epstein Barr virus (EBV) early antigen. The test system is not designed to differentiate between antibodies to the R and D components.

False negative results may occur in immunosuppressed patients.

The performance characteristics of this assay have not been established for Burkitt’s Lymphoma, nasopharyngeal carcinoma, and lymphoproliferative disorders.

The performance has been established for the aid in the diagnosis of EBV-associated infectious mononucleosis.

Reference Range

Included with report

Clinical Significance

Diagnosis of Epstein Barr virus (EBV) infectious mononucleosis in cases when heterophile antibody test results are negative and EBV-specific serologic testing is inconclusive

Aiding in the diagnosis of type 2 or type 3 nasopharyngeal carcinoma (NPC)

This test is not useful for screening patients for NPC.

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
Epstein-Barr Virus Early Antigen, IgG, Serum

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.