Prostaglandin D2, Plasma

Message

Sendout, Mayo test code: FD2PG

Test Code

LAB5210738

Alias/See Also

FD2PG
PGD2
Prostaglandins
Prostaglandins PGD2

CPT Codes
84150

Preferred Specimen

3 mL serum from a red tube

Patient Preparation
Patient should NOT be on any aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.

Minimum Volume

1 mL

Other Acceptable Specimens

Serum gel tube

Instructions

Separate immediately and send 3 mL of serum frozen in a plastic vial.

Transport Container

Plastic vial

Transport Temperature

Frozen

Specimen Stability

Frozen:60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis: NA
Lipemia: Mild reject; Gross reject
Icterus: Mild reject; Gross reject
Other: Specimens other than Serum or Plasma EDTA. Test is strict frozen.

Methodology
Radioimmunoassay (RIA) Following Extraction of Specimens

FDA Status
Approved

Setup Schedule

Monday through Friday

Report Available

10-14 days

Reference Range

Included with report

Clinical Significance

Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and Indomethacin.

Performing Laboratory
Mayo Clinic Laboratories, Inter Science Institute

Additional Information
Prostaglandin D2 (PGD2)

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.