Prostaglandin D2, Urine

Message

Sendout, Mayo test code: FPD2U

Test Code

LAB5210739

Alias/See Also

D2 Urine
PG D2
Prostaglandins D2
Prostaglandins
FPD2U

CPT Codes
84150

Preferred Specimen

10 mL random urine (no preservative)

Minimum Volume

5 mL

Instructions

1. Collect random urine (NO preservative).
2. Freeze immediately and send specimen frozen in the plastic, 10-mL urine tube (T068)

Transport Container

Plastic, 10-mL tube

Transport Temperature

Frozen

Specimen Stability

Frozen: 180 days

Methodology
Direct EIA/ELISA

FDA Status
Approved

Setup Schedule

Upon receipt

Report Available

10-14 days

Reference Range

Included with report

Clinical Significance

Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2 and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.

Performing Laboratory
Mayo Clinic Laboratories, Inter Science Institute

Additional Information
Prostaglandin D2 (PG D2), Urine

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.