2,3-Dinor 11B-Prostaglandin F2A, Urine, 24-hour

Message

Sendout, Mayo test code: 23BPT

Test Code

LAB5210234

Alias/See Also

11 Beta-Prostaglandin F2 Alpha
11BPG
2,3 11 Beta-Prostaglandin F2 Alpha
23BPG
BPG2
Mastocytosis
Prostaglandin
23BPT
23
BPT23

CPT Codes
84150, 82570

Preferred Specimen

5 mL urine collected from a 24-hour urine container.

Patient Preparation
Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAID) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen.

Minimum Volume

4 mL

Other Acceptable Specimens

URINE PRESERVATIVE COLLECTION OPTIONS

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient	No
Refrigerate	Preferred
Frozen	OK
50% Acetic Acid	OK
Boric Acid	OK
Diazolidinyl Urea	No
6M Hydrochloric Acid	No
6M Nitric Acid	No
Sodium Carbonate	OK
Thymol	No
Toluene	No

Instructions

1. Collect urine for 24 hours.
2. No preservative preferred.

Transport Container

Plastic, 5-mL tube

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated (preferred): 14 days
Frozen: 30 days
Ambient: 8 hours

Methodology
T23BP: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CRT24: Enzymatic Colorimetric Assay

FDA Status
Approved

Setup Schedule

Tuesday, Thursday

Report Available

3-8 days

Limitations

Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha (2,3 BPG) in urine are not specific for systemic mast cell disease and may be found in patients with angioedema, diffuse urticaria, or myeloproliferative diseases in the absence of diffuse mast cell proliferation.

Systemic mast cell disease is a heterogeneous disease, and some patients may not have elevated 2,3 BPG in urine.

Reference Range

Included with report

Clinical Significance

Screening for mast cell activation disorders including systemic mastocytosis using 24-hour urine specimens

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, 24 Hour, Urine

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.