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Individual Tests: Cortisol Baseline Cortisol 30 minutes Cortisol 60 minutes
MessageChemistry
Test Code
XXX9
Alias/See Also
ACTH Stimulation, Rapid ACTH Test, Cortisol Response Test
CPT Codes
82533
Includes
Cortisol
Preferred Specimen
Draw one Gold top tube for each timed draw: Baseline, 30' and 60' post Cortrosyn
1mL serum per draw
1mL serum per draw
Minimum Volume
Per timed draw:
Whole blood: 700 uL (two full red or two light-green top microtainers)
Serum/Plasma: 300 uL
Whole blood: 700 uL (two full red or two light-green top microtainers)
Serum/Plasma: 300 uL
Other Acceptable Specimens
Red Top tube
Instructions
Patients taking cortisone, hydrocortisone or any other corticosteroid should omit the pre-test does on the day of testing.
Testing related to Cortrosyn administration.
The stimulation dose is either 0.250 mg or 1 mcg. Unless otherwise specified in the physician orders, 0.250 mg Cortrosyn will be used to stimulate the adrenal cortex and the dose will be
administered intravenously by the nurse, pathologist or physician. Any variation from these 2 doses must be pre-approved by the Pathologist.
Cortrosyn (Cosyntropin) is obtained from Pharmacy. Pathologist, Physician or IV Nurse will administer Cortrosyn after a "baseline" sample is drawn. Subsequent cortisol samples are
drawn at 30 and 60 minutes post infusion.
OUTPATIENT
Outpatient testing available at Hoag Infusion Centers in Newport Beach and Irvine.
Must be scheduled with the infusion centeres: Newport Infusion Center at 949-764-8080 x2 or Irvine Infusion Center at 949-557-0200
INPATIENT
Test must be scheduled with lab, call x45600. Inpatient testing will be scheduled between 8:30 am and 5:00 pm if the Pathologist will be administering the Cortrosyn. Prefer to schedule INPATIENTS in the AM.
COMPUTER ORDER ENTRY:
Order in SCM using Order Set "CORTROSYN STIMULATION TEST"
The Order Set will include the following items:
CORTISOL,BASELINE (CORBAS)
CORTISOL-INJECT DRUG (INJCOR)
CORTISOL, 30MIN (COR30M)
CORTISOL, 60MIN (COR60M)
Physicians may order additional tests, such as:
Baseline ACTH @NIC and ALDOSTERONE @NIC.
a. If order is placed in SQ, order any additional tests indicating "draw time" as an Item
Comment, i.e. "baseline level ACTH".
b. If order is placed in SCM, order the additional tests and indicate the "draw time" in Special Instrucitons.
COMPUTER DOWNTIME PROCEDURE:
If the Hospital Computer system is down, the above 4 items in the Order Set are ordered in Sunquest. Order the Baseline and Inject Drug together. Specify "draw times" for 30 minutes apart for the 30 and 60 minute draws, appending draw time i.e. "30 min post" and "60 min post" as a comment to each order in Sunquest. Use Priority "Timed" to get separate Acc.Nos.for the 3 orders placed.
LAB:
Refer to General Laboratory Systems Manual doc #13-01-400.
CORBAS: charges for the Baseline Cortisol and the 30-Minute Cortisol
(Pre and Post injection), CPT 80400
COR60M: charges for the 60-Minute Cortisol, CPT 82533
The Injection is charged through Pharmacy
Testing related to Cortrosyn administration.
The stimulation dose is either 0.250 mg or 1 mcg. Unless otherwise specified in the physician orders, 0.250 mg Cortrosyn will be used to stimulate the adrenal cortex and the dose will be
administered intravenously by the nurse, pathologist or physician. Any variation from these 2 doses must be pre-approved by the Pathologist.
Cortrosyn (Cosyntropin) is obtained from Pharmacy. Pathologist, Physician or IV Nurse will administer Cortrosyn after a "baseline" sample is drawn. Subsequent cortisol samples are
drawn at 30 and 60 minutes post infusion.
OUTPATIENT
Outpatient testing available at Hoag Infusion Centers in Newport Beach and Irvine.
Must be scheduled with the infusion centeres: Newport Infusion Center at 949-764-8080 x2 or Irvine Infusion Center at 949-557-0200
INPATIENT
Test must be scheduled with lab, call x45600. Inpatient testing will be scheduled between 8:30 am and 5:00 pm if the Pathologist will be administering the Cortrosyn. Prefer to schedule INPATIENTS in the AM.
COMPUTER ORDER ENTRY:
Order in SCM using Order Set "CORTROSYN STIMULATION TEST"
The Order Set will include the following items:
CORTISOL,BASELINE (CORBAS)
CORTISOL-INJECT DRUG (INJCOR)
CORTISOL, 30MIN (COR30M)
CORTISOL, 60MIN (COR60M)
Physicians may order additional tests, such as:
Baseline ACTH @NIC and ALDOSTERONE @NIC.
a. If order is placed in SQ, order any additional tests indicating "draw time" as an Item
Comment, i.e. "baseline level ACTH".
b. If order is placed in SCM, order the additional tests and indicate the "draw time" in Special Instrucitons.
COMPUTER DOWNTIME PROCEDURE:
If the Hospital Computer system is down, the above 4 items in the Order Set are ordered in Sunquest. Order the Baseline and Inject Drug together. Specify "draw times" for 30 minutes apart for the 30 and 60 minute draws, appending draw time i.e. "30 min post" and "60 min post" as a comment to each order in Sunquest. Use Priority "Timed" to get separate Acc.Nos.for the 3 orders placed.
LAB:
Refer to General Laboratory Systems Manual doc #13-01-400.
CORBAS: charges for the Baseline Cortisol and the 30-Minute Cortisol
(Pre and Post injection), CPT 80400
COR60M: charges for the 60-Minute Cortisol, CPT 82533
The Injection is charged through Pharmacy
Specimen Stability
Refrigerated: 5 days
Frozen: 4 weeks
Frozen: 4 weeks
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed, contaminated, not enough volume
FDA Status
Approved
Setup Schedule
Everyday
Report Available
Same day
Reference Range
See individual tests included in panel
Performing Laboratory
Hoag Newport
