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Individual Tests: Cortisol Baseline Cortisol 30 minutes Cortisol 60 minutes
MessageChemistry
Test Code
XXX9
Alias/See Also
ACTH Stimulation, Rapid ACTH Test, Cortisol Response Test
Includes
Cortisol
Preferred Specimen
Three samples for Cortisol levels: Baseline, 30' and 60' postcortrosyn.
Draw one Gold top tube for each timed draw.
1 ml serum needed per draw.
Draw one Gold top tube for each timed draw.
1 ml serum needed per draw.
Minimum Volume
Per timed draw:
Whole blood: 700 uL (two full red or two light-green top microtainers)
Serum/Plasma: 300 uL
Whole blood: 700 uL (two full red or two light-green top microtainers)
Serum/Plasma: 300 uL
Other Acceptable Specimens
Red Top tube
Instructions
Patients taking cortisone, hydrocortisone or any other corticosteroid
should omit the pre-test does on the day of testing.
OUTPATIENTS
Outpatient testing available at Hoag Infusion Centers in Newport Beach and Irvine.
Must be scheduled with the infusion centeres: Newport Infusion Center at 949-764-8080x2 or Irvine Infusion Center at 949-557-0200
INPATIENTS
Test must be scheduled with lab, call x45600.
Inpatient testing will be scheduled between 8:30 am and 5:00 pm
if the Pathologist will be administering the Cortrosyn.
Prefer to schedule INPATIENTS in the AM.
Testing related to Cortrosyn administration.
The stimulation dose is either 0.250 mg or 1 mcg.
Unless otherwise specified in the physician orders, 0.250 mg Cortrosyn
will be used to stimulate the adrenal cortex and the dose will be
administered intravenously by the nurse, pathologist or physician.
Any variation from these 2 doses must be pre-approved by the Pathologist.
Cortrosyn (Cosyntropin) is obtained from Pharmacy.
Pathologist, Physician or IV Nurse will administer Cortrosyn after
a "baseline" sample is drawn. Subsequent cortisol samples are
drawn at 30 and 60 minutes post infusion.
LAB: Coordinate with venipuncture.
COMPUTER ORDER ENTRY:
Order in SCM using Order Set "CORTROSYN STIMULATION TEST"
The Order Set will include the following items:
CORTISOL,BASELINE (CORBAS)
CORTISOL-INJECT DRUG (INJCOR)
CORTISOL, 30MIN (COR30M)
CORTISOL, 60MIN (COR60M)
Physicians may order additional tests, such as:
Baseline ACTH @NIC and ALDOSTERONE @NIC.
a. If order is placed in SQ, order any additional tests
indicating "draw time" as an Item Comment,
i.e. "baseline level ACTH".
b. If order is placed in SCM, order the additional tests
and indicate the "draw time" in Special Instrucitons.
COMPUTER DOWNTIME PROCEDURE:
If the Hospital Computer system is down, the above 4 items in
the Order Set are ordered in Sunquest. Order the Baseline and
Inject Drug together. Specify "draw times" for 30 minutes apart for
the 30 and 60 minute draws, appending draw time i.e. "30 min post"
and "60 min post" as a comment to each order in Sunquest.
Use Priority "Timed" to get separate Acc.Nos.for the 3 orders placed.
LAB:
Refer to General Laboratory Systems Manual doc #13-01-400.
Pricing information is available by accessing the excel spreadsheet on the
L-share drive at the following path:
L:\LAB\00 Departments\10 Support_Services_Venipuncture_Front_office\
03 Staff\FRONT OFFICE\Affinity Chargemaster Laboratory\Lab Pricing Lookup
CORBAS: charges for the Baseline Cortisol and the 30-Minute Cortisol
(Pre and Post injection), CPT 80400
COR60M: charges for the 60-Minute Cortisol, CPT 82533
The Injection is charged through Pharmacy
should omit the pre-test does on the day of testing.
OUTPATIENTS
Outpatient testing available at Hoag Infusion Centers in Newport Beach and Irvine.
Must be scheduled with the infusion centeres: Newport Infusion Center at 949-764-8080x2 or Irvine Infusion Center at 949-557-0200
INPATIENTS
Test must be scheduled with lab, call x45600.
Inpatient testing will be scheduled between 8:30 am and 5:00 pm
if the Pathologist will be administering the Cortrosyn.
Prefer to schedule INPATIENTS in the AM.
Testing related to Cortrosyn administration.
The stimulation dose is either 0.250 mg or 1 mcg.
Unless otherwise specified in the physician orders, 0.250 mg Cortrosyn
will be used to stimulate the adrenal cortex and the dose will be
administered intravenously by the nurse, pathologist or physician.
Any variation from these 2 doses must be pre-approved by the Pathologist.
Cortrosyn (Cosyntropin) is obtained from Pharmacy.
Pathologist, Physician or IV Nurse will administer Cortrosyn after
a "baseline" sample is drawn. Subsequent cortisol samples are
drawn at 30 and 60 minutes post infusion.
LAB: Coordinate with venipuncture.
COMPUTER ORDER ENTRY:
Order in SCM using Order Set "CORTROSYN STIMULATION TEST"
The Order Set will include the following items:
CORTISOL,BASELINE (CORBAS)
CORTISOL-INJECT DRUG (INJCOR)
CORTISOL, 30MIN (COR30M)
CORTISOL, 60MIN (COR60M)
Physicians may order additional tests, such as:
Baseline ACTH @NIC and ALDOSTERONE @NIC.
a. If order is placed in SQ, order any additional tests
indicating "draw time" as an Item Comment,
i.e. "baseline level ACTH".
b. If order is placed in SCM, order the additional tests
and indicate the "draw time" in Special Instrucitons.
COMPUTER DOWNTIME PROCEDURE:
If the Hospital Computer system is down, the above 4 items in
the Order Set are ordered in Sunquest. Order the Baseline and
Inject Drug together. Specify "draw times" for 30 minutes apart for
the 30 and 60 minute draws, appending draw time i.e. "30 min post"
and "60 min post" as a comment to each order in Sunquest.
Use Priority "Timed" to get separate Acc.Nos.for the 3 orders placed.
LAB:
Refer to General Laboratory Systems Manual doc #13-01-400.
Pricing information is available by accessing the excel spreadsheet on the
L-share drive at the following path:
L:\LAB\00 Departments\10 Support_Services_Venipuncture_Front_office\
03 Staff\FRONT OFFICE\Affinity Chargemaster Laboratory\Lab Pricing Lookup
CORBAS: charges for the Baseline Cortisol and the 30-Minute Cortisol
(Pre and Post injection), CPT 80400
COR60M: charges for the 60-Minute Cortisol, CPT 82533
The Injection is charged through Pharmacy
Specimen Stability
Refrigerated: 5 days
Frozen: 4 weeks
Frozen: 4 weeks
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed, contaminated, not enough volume
FDA Status
Approved
Setup Schedule
Everyday
Report Available
Same day
Reference Range
See individual tests included in panel
Performing Laboratory
Hoag Newport
