Topiramate Level

Message

Sendout, Mayo test code:TOPI

Test Code

LAB498

Alias/See Also

Topiramate (Topamax)
Topamax (Topiramate)
TOPI

CPT Codes
80201

Preferred Specimen

1 ml serum from a red tube. SERUM GEL TUBE IS UNACCEPTABLE.

Minimum Volume

0.5 mL

Instructions

1. Draw blood immediately before next scheduled dose.
2. Centrifuge and aliquot serum into plastic vial; within 2 hours of collection.

Transport Container

Plastic vial

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated (preferred): 28 days
Ambient: 28 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis: Mild OK; Gross OK
Lipemia: Mild OK; Gross OK
Icterus: Mild OK; Gross OK
Other Serum gel tube, whole blood

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

FDA Status
Approved

Setup Schedule

Monday through Friday

Report Available

1-2 days

Limitations

This test cannot be performed on whole blood.

Reference Range

Included with report

Clinical Significance

Monitoring serum concentrations of topiramate

Assessing compliance

Assessing potential toxicity

Performing Laboratory
Mayo Clinic Laboratories, Rochester, Minnesota

Additional Information
Topiramate, Serum

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.