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PROTEIN, URINE, RANDOM
MessageChemistry
Test Code
LAB439
Alias/See Also
Urine, UPRO
CPT Codes
84156
Includes
Protein, Urine
Preferred Specimen
Urine specimen
Minimum Volume
300 uL urine
Instructions
LAB: Mix well. Pour 5 mL aliquot and centrifuge.
Specimen Stability
Room Temperature 18–28 °C (64–82 °F) ≤ 4 hours
Refrigerated 2–8 °C (36–46 °F) ≤ 3 days
Refrigerated 2–8 °C (36–46 °F) ≤ 3 days
Methodology
Colorimetric
FDA Status
Approved
Setup Schedule
Everyday
Report Available
Same day
Limitations
Low levels (<35 mg/dL) of Bence Jones or light chain proteins may not be detected. Elevated levels of Bence Jones or
light chain proteins may predict approximately 40% lower concentrations than pyrogallol red or turbidimetric methods.
Refer to the Recovery table.
• Very dilute urine samples (specific gravity ≤1.010) may yield artificially high 24-hour protein concentrations in large
volume (>2500 mL) samples.
• Very concentrated (specific gravity ≥1.025) urine samples may yield artificially low 24-hour protein concentrations in
large volume (>2500 mL) samples.
• Certain drugs and clinical conditions are known to alter urine protein concentration in vivo. For additional information,
refer to one of the published summaries.
light chain proteins may predict approximately 40% lower concentrations than pyrogallol red or turbidimetric methods.
Refer to the Recovery table.
• Very dilute urine samples (specific gravity ≤1.010) may yield artificially high 24-hour protein concentrations in large
volume (>2500 mL) samples.
• Very concentrated (specific gravity ≥1.025) urine samples may yield artificially low 24-hour protein concentrations in
large volume (>2500 mL) samples.
• Certain drugs and clinical conditions are known to alter urine protein concentration in vivo. For additional information,
refer to one of the published summaries.
Performing Laboratory
Hoag Newport/ Hoag Irvine
